Unlike EPO, it does not stimulate red blood cell production but instead activates tissue-protective pathways associated with cellular repair and inflammation control.
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Limited to the first 100 customers
Pre-order today to secure launch pricing
All pre-orders will ship within 1 week once production and quality verification are complete
ARA-290 10MG
Categories: Peptides, Recovery, Repair & Regeneration
ARA-290 10MG is a research-use-only peptide designed for laboratory investigation and analysis. This product is intended solely for academic or scientific applications within controlled research settings. For research use only.
$75.00
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Research Use Disclaimer
Every serious peptide company prominently displays this. Example Research Use Only All products offered by TruPeptides are intended strictly for laboratory research purposes.
Research Use Disclaimer
Every serious peptide company prominently displays this. Example Research Use Only All products offered by TruPeptides are intended strictly for laboratory research purposes.
Ara-290 10MG
Ara-290 is a synthetic peptide designed for research applications within academic and industrial scientific investigations.
This molecule represents a novel structural candidate in the study of neurobiological and metabolic processes, often explored
in controlled laboratory settings.
Research Context
Peptides like Ara-290 are frequently synthesized to investigate their potential interactions with biological targets, including
protein-protein interactions, cellular signaling pathways, or enzymatic activities. Due to their modular design and structural
versatility, such compounds are often used in drug discovery, structural biology, and fundamental biological research.
Ara-290 may be of particular interest in studies focusing on synthetic biology, peptide-based therapeutics, or synthetic
biology applications. It is important to note that Ara-290 is not intended for therapeutic, cosmetic, or diagnostic use.
Research Overview
Ara-290 is characterized by its unique amino acid sequence and potential to engage with various biological macromolecules.
Its research utility lies in its ability to serve as a tool for probing specific biochemical interactions, often utilized in
conjunction with advanced biochemical assays, crystallography, and computational modeling. As a research chemical, it is
employed by academic researchers, pharmaceutical scientists, and biotechnological innovators to advance understanding in
fields such as protein engineering, drug design, or synthetic biology.
Key Research Focus Areas
- Protein-protein interaction studies
- Structural biology and peptide design optimization
- Investigations into metabolic pathways and synthetic biology applications
- Development of novel bioorthogonal labeling agents
- Evaluation of peptide-based synthetic scaffolds for bioengineering
Ara-290 is provided for research purposes only and must be handled with the same caution as other sensitive research chemicals.
This product is intended solely for use in academic, laboratory, or industrial research settings, not for any form of human or
animal consumption or commercial application.
| Safety Note | Handling Instructions |
|---|---|
| Handle with care: Ara-290 should be stored in a secure, dry, and temperature-controlled environment. | Store at –20°C or lower when not in use. Ensure proper labeling and containment to prevent exposure. |
| Biological hazard: This compound may interact with biological systems and could pose risks if misused. | Use only in approved laboratory settings with appropriate safety measures, including personal protective equipment. |
|
Regulatory compliance: Ara-290 is subject to research-only regulations. Failure to comply with local laws regarding its possession or use may result in legal consequences. |
Ensure adherence to all applicable regulations, including but not limited to REACH, CITES, and local import/export restrictions. |
For research use only. Not for human or animal consumption.
📚 Peer-Reviewed Study
ARA-290 (Cibinetide) and Neuropathic Pain: Effects on Nerve Repair and Inflammation
📚 Peer-Reviewed Study
ARA-290 (Cibinetide) and Neuropathic Pain: Effects on Nerve Repair and Inflammation
Introduction to ARA-290
ARA-290 (also known as cibinetide) is a synthetic peptide derived from the structure of erythropoietin (EPO).
Research Objective
The referenced study aimed to evaluate the therapeutic potential of ARA-290 in treating small fiber neuropathy and associated pain conditions.
Researchers focused on its ability to reduce neuropathic pain while promoting nerve regeneration and functional recovery.
Study Design and Methodology
The study reviewed data from Phase II clinical trials involving patients with sarcoidosis-related neuropathy.
Outcomes included pain scores, nerve fiber density measurements, sensory thresholds, and quality of life assessments.
Key Findings — Pain Reduction and Nerve Repair
ARA-290 treatment was associated with significant reductions in neuropathic pain scores and improvements in sensory function.
Patients also showed increased corneal nerve fiber density and improved physical functioning, indicating structural and functional nerve recovery.
Mechanisms of Action
ARA-290 selectively activates the innate repair receptor (IRR), triggering anti-inflammatory and cytoprotective signaling pathways.
This results in reduced cytokine activity, inhibition of tissue damage, and stimulation of regenerative processes in nerve tissue. :contentReference[oaicite:1]{index=1}
Implications for Neurological and Inflammatory Research
These findings position ARA-290 as a key compound in research focused on neuropathy, inflammation, and tissue repair.
Its non-erythropoietic nature allows targeted activation of healing pathways without the hematological side effects of erythropoietin.
Conclusion
ARA-290 demonstrated significant improvements in neuropathic pain and nerve regeneration markers in clinical research settings.
These results support its continued investigation as a tissue-protective and anti-inflammatory peptide in neurological disorders.
Frequently Asked Questions (FAQ)
What is ARA-290?
ARA-290 is a synthetic peptide derived from erythropoietin that activates tissue repair pathways without affecting red blood cell production.
What does ARA-290 do?
It reduces inflammation, supports nerve repair, and improves symptoms of neuropathic pain in research models.
What did the study show?
The study showed reduced pain scores, improved nerve fiber density, and enhanced quality of life in treated subjects.
Is ARA-290 the same as erythropoietin?
No. It is derived from erythropoietin but does not stimulate red blood cell production.
Is this based on human research?
Yes, the referenced study includes clinical trial data in human subjects.
Study Reference
van Velzen M. et al. Expert Opin Investig Drugs. 2014;23(4):541-550.
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